Animals have been used repeatedly throughout the history of biomedical research. Even Aristotle have performed experiments on living animals. 1938 Food, drug and cosmetic act reguired safety testing of drugs on animals before they could be marketed and this was because of using diethylene glycol as a solvent in drugs. In recent years laws (2010/63/EU) have been passed in several countries to make animal testing in more humane way. Animal testing occurs regularly throughout the EU, across all of Europe there are approximately 12.1 million animal testing experiments each year. Rats and mice are the most of used animals.
Animal tests used in medical research:
In metabolic tests investigating how drugs are absorbed, metabolized and excreted by the body when dosed by different ways.
In toxicology tests investigating acute, sub-acute and chronic toxicity.
Efficacy studies test whether experimental drugs work by inducing the appropriate illness in animals.
Although animal testing makes animals suffer or even cause a painful death it has helped to develop medicines against many severe diseases like rabies, polio and HIV.
– Miikka Rosten and Laura Valli